Name
EphB2 R Antibody, HRP Conjugated
Catalog number
bs-0247R-HRP
Size
0.1ml
Price
350 EUR
Conjugation
HRP
Excitation Emission
N/A
Gene ID number
2048
Modification site
None
Swiss Prot
P29323
Target Antigen
EphB2 R
Tested applications
WB, IHC-P
French translation
anticorps
Modification
Unmodified
Clonality
Polyclonal
Concentration
1ug per 1ul
Immunogen_range
100-150/1055
Subcellular location
Extracellular
Additional conjugation
HRP Conjugated
Crossreactivity
Human, Mouse, Rat
Clone
Polyclonal antibody
Category
Conjugated Primary Antibodies
Host Organism
Rabbit (Oryctolagus cuniculus)
Recommended dilutions
WB(1:100-1000), IHC-P(1:100-500)
Purification method
This antibody was purified via Protein A.
Long name
EphB2 R Polyclonal Antibody, HRP Conjugated
Specificity
This is a highly specific antibody against EphB2 R.
Source
KLH conjugated synthetic peptide derived from human EphB2 R
Crossreactive species details
Due to limited amount of testing and knowledge, not every possible cross-reactivity is known.
Storage conditions
Keep the antibody in an aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% Gentamicin. Store refrigerated at 2 to 8 degrees Celcius for up to 1 year.
Synonyms
DRT; EK5; ERK; CAPB; Hek5; PCBC; EPHT3; Tyro5; Ephrin type-B receptor 2; Developmentally-regulated Eph-related tyrosine kinase; ELK-related tyrosine kinase; EPH tyrosine kinase 3; EPH-like kinase 5; Renal carcinoma antigen NY-REN-47; Tyrosine-protein kinase TYRO5; Tyrosine-protein kinase receptor EPH-3; EPHB2; EPTH3
Properties
If you buy Antibodies supplied by Bioss Primary Conjugated Antibodies they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.HRP conjugates are often primary rabbit polyclonal antibodies couples to the enzyme horseradish peroxidase (HRP), found in the roots of horseradish. Also monoclonal HRP conjugates are often used for Western Blot.
Antigen background
Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.