Rabbit Anti Human EPHB2 Antibody-Non-conjugated

Rabbit Anti Human EPHB2 Antibody-Non-conjugated

Name

Rabbit Anti Human EPHB2 Antibody-Non-conjugated

Catalog number

CSB-PA007730LA01HU_50ug

Size

50ug

Price

212 EUR

Antibody isotype

IgG

Purity

>95%

Species reactivity

Human

Immunogen species

Human

UniProt ID

P29323

French translation

anticorps

Conjugation

Non-conjugated

Purification method

Protein G purified

Clonality

Polyclonal antibody

Short name of the antigen

Actin, cytoplasmic 2

Synonym name

EPHB2 Human Antibody

Latin name

Oryctolagus cuniculus

Antibody category

Polyclonal Antibodies

Format

Liquid, diluted in buffer

Long name

Rabbit Antibody against Human EPHB2, Non-conjugated

Alias

CAPB; DRT; EK5; EPH receptor B2; Ephrin type-B receptor 2

Tested applications & recommended dilutions

ELISA,IHC,IF;Recommended dilution:IHC:1:20-1:200,IF:1:50-1:200

Immunogen type

Recombinant human Ephrin type-B receptor 2 protein (261-465AA)

Buffer composition

Preservative: 0.03% Proclin 300, Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Description

This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.Antibody against the Hu protein or peptide or recombinant supplied in 1 volumes. Ask for quote if you need bulk.

Shipping and storage

EPHB2 Antibody is shipped on ice packs and upon receipt should be stored at -20 or -80 degrees Celsius. We recommend that you prepare the working aliquots in advance so that freez-thaw cycles are avoided. Do not expose the antibodies to drirect bright light, especially the labeled ones as most conjugates are light sensitive.

About

Rabbits are used for polyclonal antibody production by Cusabio. Rabbit antibodies are very stable and can be stored for several days at room temperature. Cusabio adds sodium azide and glycerol to enhance the stability of the rabbit polyclonal antibodies. Anti-human, anti mouse antibodies to highly immunogenic selected peptide sequences are" monoclonal like" since the epitope to which they are directed is less than 35 amino acids long.

Properties

If you buy Antibodies supplied by Cusabio they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.Human proteins, cDNA and human recombinants are used in human reactive ELISA kits and to produce anti-human mono and polyclonal antibodies. Modern humans (Homo sapiens, primarily ssp. Homo sapiens sapiens). Depending on the epitopes used human ELISA kits can be cross reactive to many other species. Mainly analyzed are human serum, plasma, urine, saliva, human cell culture supernatants and biological samples.

Background

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Functions in axon guidance during development. Involved in the guidance of commissural axons, that form a major interhemispheric connection between the 2 temporal lobes of the cerebral cortex. Also involved in guidance of contralateral inner ear efferent growth cones at the midline and of retinal ganglion cell axons to the optic disk. In addition to axon guidance, also regulates dendritic spines development and maturation and stimulates the formation of excitatory synapses. Upon activation by EFNB1, abolishes the ARHGEF15-mediated negative regulation on excitatory synapse formation. Controls other aspects of development including angiogenesis, palate development and in inner ear development through regulation of endolymph production. Forward and reverse signaling through the EFNB2/EPHB2 complex regulate movement and adhesion of cells that tubularize the urethra and septate the cloaca. May function as a tumor suppressor.