Name
AZD6244,ERK kinase inhibitor
Catalog number
SIH-495-5MG
Size
5 mg
Price
280 EUR
Molecular Weight
457.7
Storage Temperature
-20°C
Purity
≥98%
Product Type
Inhibitor
CAS No.
606143-52-6
Shipping Temperature
Shipped Ambient
MolecularFormula
C17H15BrClFN4O3
Category
Small Molecules
Appearance
White to off-white solid
Solubility
Soluble in DMSO (92 mg/ml at 25 °C), water (
Research Area(s)
Cell Signaling , Cancer , Apoptosis , Cancer Growth Inhibitors , Tyrosine Kinase Inhibitors
Description
Tissue, pathway, proteinase, peptidase, protease ,acrosin, lipoprotein, activator, caspase, trypsin, papain, esterase inhibitors are proteins or receptor ligands or receptor antagonists that bind to an enzyme receptor and decreases its activity. Since blocking an enzyme's activity can kill a pathogen or correct a metabolic imbalance, many drugs are enzyme inhibitors. Not all receptor antagonist that bind to enzymes are inhibitors; enzyme activator ligands or agonists bind to enzymes and increase their enzymatic activity, while enzyme substrates bind and are converted to products in the normal catalytic cycle of the enzyme.