Name
anti-PHB2 Antibody
Catalog number
30-396
Size
50 ug
Price
180 EUR
GENE symbol
PHB2
NCBI GENE nr
11331
Ab raised in
Rabbit
Protein nr
Q99623
KDa
33 kDa
Omim nr
6005854
Quantity per ml
1 mg/ml
Ncbi nr
NP_009204
French translation
anticorps
Type
Polyclonal
Vial with antibody
Lyophilized
Source
Homo sapiens
Antigene name
prohibitin 2
Antibodie's label
unlabelled serum
Works with
Human, Mouse, Rat
Immuno application
ELISA, Western Blot
Gene names
PHB2, BAP, BCAP37, Bap37, MGC117268, PNAS-141, REA, p22
Purity
Antibody is purified by peptide affinity chromatography method.
Antigen
Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PHB2.
Suspention, pH, azide
Antibody is lyophilized in PBS buffer with 2% sucrose. Add 50 μL of distilled water. Final antibody concentration is 1 mg/mL.
Properties
If you buy Antibodies supplied by proscience they should be stored frozen at - 24°C for long term storage and for short term at + 5°C.
Description
This antibody needs to be stored at + 4°C in a fridge short term in a concentrated dilution. Freeze thaw will destroy a percentage in every cycle and should be avoided.
Keep at
For short periods of storage (days) store at 4 grades C. For longer periods of storage, store PHB2 antibody at -20 grades C. As with any antibody avoid repeat freeze-thaw cycles.
Antibody advice
PHB2 antibody can be used for detection of PHB2 by ELISA at 1:62500. PHB2 antibody can be used for detection of PHB2 by western blot at 0.5 ug/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.
Gene info
PHB2 acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases (By similarity). It functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. PHB2 competes with NCOA1 for modulation of ER transcriptional activity. It probably involved in regulating mitochondrial respiration activity and in aging.